Working in our lab

We are happy to receive applications from motivated and enthusiastic researchers for postdoc and PhD positions, as well as from Masters and Bachelor students. Our research is multi-facetted and, for the most part, interdisciplinary in nature. The members of our lab and our collaborators have diverse scientific backgrounds, ranging from biology, biochemistry ,and physical chemistry to computer science and theoretical physics.  If you are an experimentalist attracted by problems that require integrating several types of approaches, or a quantitatively trained scientist who seeks to work at the interface between theory and experiment, you may be interested in our work.

 

Specific job offers:

 

Postdoc in Molecular Systems Biology

 

We invite a molecular biologist or biochemist with an interest in questions of gene regulation to join our team at the Gene Center Munich. Our lab studies regulatory processes in Drosophila development at a systems level, using a combination of biochemical, genomic, and computational approaches. Current research is focused on understanding how cis-regulatory elements ‘compute’ expression to produce defined spatio-temporal patterns, the architecture and function of core promoters, and the regulatory role of chromatin. Our long-term goal is an integrated quantitative model of transcriptional regulation that realistically captures the underlying molecular mechanisms.

The Gene Center of the LMU Munich is an interdisciplinary institute whose 16 independent groups study gene regulation at every level, from molecular mechanism to biological system. The Center is located on the biomedical research campus in Munich-Großhadern and provides a dynamic, interactive, and internationally diverse scientific environment.

Your tasks: You will work on projects aimed at tracking regulatory events at high resolution and throughput, using methods such as next generation sequencing (ChIP-, RNA-, DNase-Seq) and reporter assays to test synthetic regulatory elements. The initial focus will be to construct and measure the activity of a large library of synthetic core promoters using high throughput robotics. You will also help coordinate and manage lab activities in these areas and advise PhD students.

Your profile: PhD in molecular biology, biochemistry, biotechnology/bioengineering, or similar qualification, with substantial experience in functional genomic approaches and cell culture techniques; experience with synthetic biology and high throughput robotics is a plus. Our ideal candidate has excellent technical skills, is well organized yet creative and fearless in optimizing and developing new techniques, and enjoys working within a multi-disciplinary team of scientists.

The salary is according to the TV-L and depends on your qualification and experience. The position is available immediately and will initially be for two years, but we are interested in a longer-term relationship. The University of Munich is an equal opportunity employer.

Please send a single pdf-file with your application (including cover letter, CV, degrees, references) by March 15, 2014 to:

Prof. Dr. Ulrike Gaul

email: office-gaul@genzentrum.lmu.de

Genzentrum, Ludwig-Maximilians-Universität München

Feodor-Lynen-Strasse 25, 81377 München

http://www.genzentrum.lmu.de

 

 

 

Postdoc in Computational Biology / Bioinformatics of Gene Regulation

 

We invite a computational biologist or bioinformatician with a strong interest in questions of gene regulation to join our team at the Gene Center Munich. Our lab studies regulatory processes in Drosophila development at a systems level, using a combination of biochemical, genomic, and computational approaches. Current research is focused on understanding how cis-regulatory elements ‘compute’ expression to produce defined spatio-temporal patterns, the architecture and function of core promoters, and the regulatory role of chromatin. Our long-term goal is an integrated quantitative model of transcriptional regulation that realistically captures the underlying molecular mechanisms.

The Gene Center of the LMU Munich is an interdisciplinary institute whose 16 independent groups study gene regulation at every level, from molecular mechanism to biological system. The Center provides a dynamic, interactive, and internationally diverse scientific environment, located within a vibrant biomedical research campus in Munich-Großhadern.

Your tasks: Computational analysis of a diverse range of genome-scale experimental data aimed at tracking regulatory processes, in particular next generation sequencing (RNA-, ChIP-, MNase-Seq) and high throughput assays to test synthetic regulatory elements. Working closely with experimentalists and supported by collaborating computational groups, you will be responsible for developing and implementing appropriate strategies at all levels of analysis, from quality control and statistical evaluation to correlating, integrating and visualizing results. An important task will be to set up an improved system for data and workflow management using tools such as openBIS, Galaxy, and KNIME.

Your profile: PhD in computational biology, bioinformatics, (bio-)statistics, (bio-)physics or similar qualification, with a strong background in data analysis and data management, preferably of genomic or proteomic data. Our ideal candidate has excellent analytical and technical/programming skills, combines a good organizational sense and attention to detail with creativity and fearlessness in exploring complex data, and enjoys working within a multi-disciplinary team of scientists.

The salary is according to the TV-L and depends on your qualification and experience. The position is available immediately and will initially be for two years, but we are interested in a longer-term relationship. The University of Munich is an equal opportunity employer.

Please send a single pdf-file with your application (including cover letter, CV, degrees, references) by February 28, 2014 to:

Prof. Dr. Ulrike Gaul

email: office-gaul@genzentrum.lmu.de

Genzentrum, Ludwig-Maximilians-Universität München

Feodor-Lynen-Strasse 25, 81377 München

http://www.genzentrum.lmu.de